The Science Behind TissueCypher®
Cancer is a System, Not a Single Cell Type
Tumors are composed of many interacting cell types, including malignant cells, immune cells such as macrophages, stromal cells such as fibroblasts and endothelial cells, as well as cancer stem cells. All of these cell types impact cancer development, tumor progression, responses to therapy, and ultimately, patient outcomes. The majority of cancer diagnoses are currently made by pathologists viewing tissues on glass slides via light microscopy (anatomic pathology). While valuable, this approach is focused on the morphology of malignant cells and is limited in its ability to evaluate multiple biomarkers and cell types within the tumor system.